SCHEMBL24816905

SCHEMBL24816905

Cc1ccc(C2CCC(=O)NC2=O)cc1C

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 19/20 0.60
▸ DDB1 Q16531 18/20 0.60
▸ POLB P06746 1/20 0.55
▸ GSPT1 P15170 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25810649 0.88 CRBN (0.57) CRBNDDB1POLBGSPT1
SCHEMBL27362710 0.88 CRBN (0.57) CRBNDDB1POLBGSPT1
SCHEMBL25504172 0.86 CRBN (0.56) CRBNDDB1POLBGSPT1
SCHEMBL24753405 0.86 CRBN (0.63) CRBNDDB1POLBGSPT1
SCHEMBL24352125 0.83 CRBN (0.52) CRBNDDB1POLBGSPT1
SCHEMBL25026923 0.81 CRBN (0.70) CRBNDDB1POLBGSPT1
SCHEMBL7828080 0.81 CRBN (0.70) CRBNDDB1POLBGSPT1
SCHEMBL25026926 0.81 CRBN (0.70) CRBNDDB1POLBGSPT1
SCHEMBL21934060 0.79 CRBN (0.68) CRBNDDB1POLB
SCHEMBL30883502 0.79 CRBN (0.51) CRBNDDB1POLBGSPT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022268229-A1 PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE 和径医药科技(上海)有限公司 2022-12-29 — — WO disclosed
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