Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362710 | 1.00 | CRBN (0.57) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL24816905 | 0.88 | CRBN (0.60) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL25026921 | 0.84 | CRBN (0.54) | CRBNDDB1POLB | |
| SCHEMBL31216627 | 0.84 | CRBN (0.56) | CRBNDDB1POLB | |
| SCHEMBL23551626 | 0.83 | POLB (0.54) | CRBNDDB1POLB | |
| SCHEMBL27051455 | 0.83 | CRBN (0.52) | CRBNDDB1POLB | |
| SCHEMBL29013196 | 0.81 | CRBN (0.53) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL24753405 | 0.81 | CRBN (0.63) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL25504172 | 0.81 | CRBN (0.56) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL30479047 | 0.80 | CRBN (0.52) | CRBNDDB1POLBGSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054591-A1 | RAPIDLY ACCELERATED FIBROSARCOMA (RAF) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| WO-2023116934-A1 | KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |