Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24816905 | 0.86 | CRBN (0.60) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL24753405 | 0.82 | CRBN (0.63) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL25810649 | 0.81 | CRBN (0.57) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL27362710 | 0.81 | CRBN (0.57) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL25213082 | 0.79 | CRBN (0.52) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL25026923 | 0.78 | CRBN (0.70) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL8190472 | 0.78 | CRBN (0.70) | CRBNDDB1POLB | |
| SCHEMBL7828080 | 0.78 | CRBN (0.70) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL25026926 | 0.78 | CRBN (0.70) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL24352125 | 0.76 | CRBN (0.52) | CRBNDDB1POLBGSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086399-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |