SCHEMBL24817

SCHEMBL24817

[c]1cccc2[nH]c3ccccc3c12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
GPR3 P46089 2/20 0.54
HSD17B10 Q99714 2/20 0.54
KDM4E B2RXH2 4/20 0.46
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
AHR P35869 2/20 0.46
LMNA P02545 2/20 0.46
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
HTT P42858 1/20 0.46
ATM Q13315 1/20 0.46
ACHE P22303 2/20 0.41
BCHE P06276 1/20 0.41
KIF11 P52732 5/20 0.39
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRA1 P14867 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRG2 P18507 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29196071 0.84 ALDH1A1 (0.61) ALDH1A1GPR3HSD17B10KDM4EHPGD
SCHEMBL2388664 0.84 ALDH1A1 (0.39) ALDH1A1GPR3HSD17B10KDM4EHPGD
SCHEMBL3232112 0.80 ALDH1A1 (0.32) ALDH1A1GPR3HSD17B10
SCHEMBL15902814 0.79 AHR (0.39) ALDH1A1GPR3HSD17B10KDM4EHPGD
SCHEMBL496747 0.77 CHUK (0.58) ALDH1A1KDM4EHPGDSMN1; SMN2ACHE
SCHEMBL18427910 0.77 ACHE (0.58) ALDH1A1HSD17B10KDM4EHPGDSMN1; SMN2
SCHEMBL15063062 0.77 ALDH1A1 (0.46) ALDH1A1GPR3HSD17B10KDM4EHPGD
SCHEMBL2470534 0.76 CDK4 (0.47) ALDH1A1GPR3HSD17B10KDM4EHPGD
SCHEMBL25140411 0.75 ALDH1A1 (0.50) ALDH1A1GPR3HSD17B10KDM4EHPGD
SCHEMBL16179644 0.75 ALDH1A1 (0.50) ALDH1A1GPR3HSD17B10KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13391 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344281-A Multiple host materials and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-07-16 CN claimed
CN-118324771-A Organic light-emitting device, electronic device, and heterocyclic compound 三星显示有限公司 2024-07-12 CN claimed
WO-2024131776-A1 BUFALIN DERIVATIVE AND PREPARATION METHOD THEREFOR, COMPOSITION, PREPARATION, AND APPLICATION 上海邈基生物科技有限公司 2024-06-27 WO claimed
CN-118239898-A Blue light material, preparation method and organic electroluminescent device 成都维拓立柔性电子技术有限公司 2024-06-25 CN claimed
WO-2024121084-A1 PREPARATION OF NITRILES MERCK PATENT GMBH (DE) 2024-06-13 WO claimed
US-12004420-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-06-04 US claimed
CN-118108717-A Organic compound and application thereof, and organic electroluminescent device comprising organic compound 北京鼎材科技有限公司 2024-05-31 CN claimed
CN-118063519-A Organic metal compound and organic electroluminescent device 吉林奥来德光电材料股份有限公司 2024-05-24 CN claimed
CN-117946085-A Phosphorescent host material, preparation method thereof and organic electroluminescent device 吉林奥来德光电材料股份有限公司 2024-04-30 CN claimed
WO-2024081739-A2 COVALENT COMPOUNDS AND USES THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2024-04-18 WO claimed
EP-0699191-A1 SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN TEXAS BIOTECHNOLOGY CORPORATION (US) 1996-03-06 EP claimed
WO-1995026347-A1 THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1995-10-05 WO claimed
WO-1994027979-A1 SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN IMMUNOPHARMACEUTICS, INC. (US) 1994-12-08 WO claimed
EP-0512020-A1 PROCESS FOR PREPARING HOMOCHIRAL AMINES AND PROCESS FOR PREPARING INTERMEDIATES FOR THE PREPARATION THEREOF Nobel Chemicals AB (SE) 1992-11-11 EP claimed
US-5086052-A Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis ABBOTT LABORATORIES (US) 1992-02-04 US claimed
WO-1991010642-A1 PROCESS FOR PREPARING HOMOCHIRAL AMINES AND PROCESS FOR PREPARING INTERMEDIATES FOR THE PREPARATION THEREOF, AND THE INTERMEDIATES PREPARED IN ACCORDANCE WITH THIS PROCESS NOBEL CHEMICALS AB (SE) 1991-07-25 WO claimed
EP-0194752-A1 Dihydropyridine alkanol amines, process for their preparation and pharmaceutical compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-09-17 EP claimed
EP-0193227-A1 Process for the preparation of arylglycidyl ethers and 3-substituted 1-alkylamino-2-propanols GIST-BROCADES N.V. (NL) 1986-09-03 EP claimed
EP-0086564-B1 ALKANOLAMINE DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-11-21 EP claimed
EP-0086564-A1 Alkanolamine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-08-24 EP claimed