Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 2/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321792 | 1.00 | RAF1 (0.36) | RAF1FFAR4HRH3RORCKDM5A | |
| SCHEMBL15778154 | 0.84 | PANK3 (0.41) | HRH3RORCKDM5AKDM4CKDM5B | |
| SCHEMBL30685543 | 0.83 | RORC (0.34) | FFAR4HRH3RORCKDM5AKDM4C | |
| SCHEMBL24818056 | 0.83 | RORC (0.34) | FFAR4HRH3RORCKDM5AKDM4C | |
| SCHEMBL3908016 | 0.81 | HTR1D (0.40) | HRH3KDM5AKDM4CKDM5BPANK3 | |
| SCHEMBL3902288 | 0.79 | ACMSD (0.41) | FFAR4HRH3PANK3 | |
| SCHEMBL24817067 | 0.79 | SLC6A2 (0.35) | RAF1HRH3KDM5AKDM4CKDM5B | |
| SCHEMBL24817083 | 0.79 | GLP1R (0.33) | RAF1FFAR4GLP1R | |
| SCHEMBL15783788 | 0.76 | MEN1 (0.38) | ACVRL1 | |
| SCHEMBL16070838 | 0.76 | ESR2 (0.38) | HRH3RORCKDM5AKDM4CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268152-A1 | GLP-1 RECEPTOR AGONIST AND COMPOSITION AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-12-29 | — | — | WO | disclosed |