Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 6/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23692608 | 0.97 | PPIA (0.39) | PPIANPFFR1NPFFR2DRD2CTSK | |
| SCHEMBL31491350 | 0.87 | SMN1; SMN2 (0.43) | PPIADRD2CTSKCTSLCTSB | |
| SCHEMBL24815894 | 0.82 | KMT2A (0.35) | PPIADRD2CTSKCTSLCACNA1H | |
| SCHEMBL2869065 | 0.80 | DRD2 (0.37) | PPIANPFFR1NPFFR2DRD2CTSK | |
| SCHEMBL20069700 | 0.80 | CACNA1H (0.37) | PPIANPFFR1NPFFR2DRD2CTSK | |
| SCHEMBL31560797 | 0.78 | CACNA1H (0.34) | NPFFR1NPFFR2DRD2CTSKCTSL | |
| SCHEMBL20147479 | 0.77 | CTSL (0.35) | PPIANPFFR1NPFFR2DRD2CTSK | |
| SCHEMBL14173595 | 0.76 | KMT2A (0.38) | PPIACTSKCTSLP2RX7MEN1 | |
| SCHEMBL56916 | 0.76 | TDP1 (0.41) | PPIADRD2CTSKCTSLP2RX7 | |
| SCHEMBL7609264 | 0.75 | MEN1 (0.37) | PPIACTSKCTSLP2RX7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074305-A1 | N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-04-10 | — | — | WO | disclosed |
| WO-2022268230-A1 | COMPOUND AS KIF18A INHIBITOR | 杭州英创医药科技有限公司 | 2022-12-29 | — | — | WO | disclosed |