SCHEMBL248183

SCHEMBL248183

NC(=O)C1CCC=CC1C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.34
EPHX1 P07099 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6219581 0.88 MAPT (0.36) MAPTEPHX1
SCHEMBL5585363 0.85 MAPT (0.37) MAPTEGLN1POLBAPEX1TDP1
SCHEMBL22390581 0.85 MAPT (0.37) MAPTEGLN1POLBAPEX1TDP1
SCHEMBL27341 0.85 MAPT (0.37) MAPTEGLN1POLBAPEX1TDP1
SCHEMBL27596921 0.84 MAPT (0.34) MAPTPOLBAPEX1TDP1
Hydrochloric Acid SCHEMBL3839089 0.83 MAPT (0.36) MAPTEGLN1POLBAPEX1TDP1
SCHEMBL16207394 0.83 MAPT (0.36) MAPTEGLN1POLBAPEX1TDP1
Bromide SCHEMBL7615302 0.83 MAPT (0.36) MAPTEGLN1POLBAPEX1TDP1
Hydrochloric Acid SCHEMBL10904239 0.83 MAPT (0.36) MAPTEGLN1POLBAPEX1TDP1
Bromide SCHEMBL8064378 0.83 MAPT (0.36) MAPTEGLN1POLBAPEX1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1987007602-A2 N-(5-SUBSTITUTED METHYLENE) PHENYL HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1987-12-17 WO claimed
JP-5155836-A None JP disclosed
US-20250136542-A1 CALCIUM SALT POLYMORPHS AS ANTI-INFLAMMATORY, IMMUNODULATORY AND ANTI-PROLIFERATIVE AGENTS IMMUNIC AG (DE) 2025-05-01 US disclosed
EP-4438591-A1 NOVEL CALCIUM SALT POLYMORPHS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS Immunic AG (DE) 2024-10-02 EP disclosed
US-12037305-B2 Calcium salt polymorphs as anti-inflammatory, immunomodulatory and anti-proliferative agents IMMUNIC AG (DE) 2024-07-16 US disclosed
EP-3765439-B1 NOVEL CALCIUM SALT POLYMORPHS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS IMMUNIC AG (DE) 2024-05-01 EP disclosed
US-11186793-B2 Protection of liquid fuels PALOX LIMITED (CY) 2021-11-30 US disclosed
US-20210017125-A1 Novel calcium salt polymorphs as Anti-Inflammatory, Immunomodulatory and Anti-Proliferatory Agents IMMUNIC AG (DE) 2021-01-21 US disclosed
EP-3765439-A1 NOVEL CALCIUM SALT POLYMORPHS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS Immunic AG (DE) 2021-01-20 EP disclosed
WO-2019175396-A1 NOVEL CALCIUM SALT POLYMORPHS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS IMMUNIC AG (DE) 2019-09-19 WO disclosed
WO-1993022280-A1 SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM BASF AKTIENGESELLSCHAFT (DE) 1993-11-11 WO disclosed
JP-H05155836-A N-PHENYLTETRAHYDROPHTHALAMIC ACID DERIVATIVE AND HERBICIDE CONTAINING THE DERIVATIVE AS ACTIVE COMPONENT CENTRAL GLASS CO LTD 1993-06-22 JP disclosed
EP-0496900-A1 N-ACYL-N-PHENYLTETRAHYDROPHTHALAMIC ACID DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT CENTRAL GLASS COMPANY, LIMITED (JP) 1992-08-05 EP disclosed
WO-1987007602-A2 N-(5-SUBSTITUTED METHYLENE) PHENYL HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1987-12-17 WO disclosed
EP-0073409-B1 N-SUBSTITUTED-TETRAHYDROISOPHTHALIMIDE DERIVATIVES NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1986-05-07 EP disclosed
EP-0031924-B1 USE OF ALCANOL-AMINE SALTS OF CYCLIC AMIDOCARBOXYLIC ACIDS AS CORROSION INHIBITORS IN AQUEOUS SYSTEMS BASF Aktiengesellschaft (DE) 1983-05-18 EP disclosed
EP-0073409-A1 N-substituted-tetrahydroisophthalimide derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1983-03-09 EP disclosed
US-4362546-A Tetrahydrophthalamide derivatives, herbicidal compositions and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-12-07 US disclosed
US-4328367-A HERBICIDE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-05-04 US disclosed
EP-0031924-A1 Use of alcanol-amine salts of cyclic amidocarboxylic acids as corrosion inhibitors in aqueous systems BASF Aktiengesellschaft (DE) 1981-07-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037305-B2 Calcium salt polymorphs as anti-inflammatory, immunomodulatory and anti-proliferative agents DHODH, CA2, FH MAPT 411/4885EPHX1 718/4885EGLN1 2849/4885
US-20210017125-A1 Novel calcium salt polymorphs as Anti-Inflammatory, Immunomodulatory and Anti-Proliferatory Agents DHODH, FH, HADHB MAPT 823/4885EPHX1 1153/4885EGLN1 3277/4885
US-20250136542-A1 CALCIUM SALT POLYMORPHS AS ANTI-INFLAMMATORY, IMMUNODULATORY AND ANTI-PROLIFERATIVE AGENTS DHODH, CA2, DPYD MAPT 305/4885EPHX1 737/4885EGLN1 2750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.