Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 6/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 4/20 | 0.32 |
| ▸ | FNTB | P49356 | 4/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CBL | P22681 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152973 | 1.00 | CBLB (0.40) | CBLBNSD2PIN1FNTAFNTB | |
| SCHEMBL24819959 | 0.89 | CBLB (0.33) | CBLBCBL | |
| SCHEMBL30152906 | 0.89 | CBLB (0.33) | CBLBCBL | |
| SCHEMBL24818671 | 0.88 | CBLB (0.39) | CBLBNSD2PIN1FNTAFNTB | |
| SCHEMBL30152790 | 0.85 | CBLB (0.44) | CBLBHCRTR1HCRTR2 | |
| SCHEMBL30152993 | 0.85 | CBLB (0.44) | CBLBHCRTR1HCRTR2 | |
| SCHEMBL24819974 | 0.85 | CBLB (0.44) | CBLBHCRTR1HCRTR2 | |
| SCHEMBL24818896 | 0.83 | CBLB (0.40) | CBLBNSD2FNTAFNTB | |
| SCHEMBL30152890 | 0.83 | CBLB (0.40) | CBLBNSD2FNTAFNTB | |
| SCHEMBL29189918 | 0.81 | CBLB (0.39) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |