Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 5/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | CBL | P22681 | 2/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 4/20 | 0.32 |
| ▸ | FNTB | P49356 | 4/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152973 | 0.88 | CBLB (0.40) | CBLBNSD2DGAT1SOAT1KCNH2 | |
| SCHEMBL24818672 | 0.88 | CBLB (0.40) | CBLBNSD2DGAT1SOAT1KCNH2 | |
| SCHEMBL30152840 | 0.88 | CBLB (0.39) | CBLBCBLSCN9A | |
| SCHEMBL24821801 | 0.88 | CBLB (0.39) | CBLBCBLSCN9A | |
| SCHEMBL30153188 | 0.87 | CBLB (0.43) | CBLBCBLSCN9A | |
| SCHEMBL24820229 | 0.87 | CBLB (0.43) | CBLBCBLSCN9A | |
| SCHEMBL30152857 | 0.87 | CBLB (0.39) | CBLB | |
| SCHEMBL29189918 | 0.87 | CBLB (0.39) | CBLB | |
| SCHEMBL24818812 | 0.81 | CBLB (0.39) | CBLBNSD2CBLACP1FNTA | |
| SCHEMBL30153053 | 0.81 | CBLB (0.39) | CBLBNSD2CBLACP1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |