Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 10/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.34 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152890 | 1.00 | CBLB (0.40) | CBLBFNTAFNTBNSD2VSIR | |
| SCHEMBL24819786 | 0.90 | S1PR1 (0.37) | CBLBVSIRCETPS1PR1S1PR3 | |
| SCHEMBL30153127 | 0.90 | S1PR1 (0.37) | CBLBVSIRCETPS1PR1S1PR3 | |
| SCHEMBL24818674 | 0.89 | VSIR (0.40) | CBLBVSIRCETPS1PR1S1PR3 | |
| SCHEMBL30153123 | 0.88 | CBLB (0.38) | CBLBFNTAFNTBNSD2CETP | |
| SCHEMBL24818895 | 0.88 | CBLB (0.38) | CBLBFNTAFNTBNSD2CETP | |
| SCHEMBL30153053 | 0.88 | CBLB (0.39) | CBLBFNTAFNTBNSD2VSIR | |
| SCHEMBL24818812 | 0.88 | CBLB (0.39) | CBLBFNTAFNTBNSD2VSIR | |
| SCHEMBL24818899 | 0.86 | CBLB (0.39) | CBLBFNTAFNTBCETP | |
| SCHEMBL30153241 | 0.86 | CBLB (0.39) | CBLBFNTAFNTBCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |