Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 3/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152848 | 1.00 | CBLB (0.40) | CBLBJAK2JAK1TYK2JAK3 | |
| SCHEMBL24818791 | 0.92 | CBLB (0.34) | CBLBVSIR | |
| SCHEMBL30153230 | 0.92 | CBLB (0.34) | CBLBVSIR | |
| SCHEMBL30153102 | 0.91 | CBLB (0.38) | CBLBVSIR | |
| SCHEMBL24819035 | 0.91 | CBLB (0.38) | CBLBVSIR | |
| SCHEMBL24818925 | 0.91 | VSIR (0.40) | CBLBCETPVSIR | |
| SCHEMBL30152788 | 0.91 | VSIR (0.40) | CBLBCETPVSIR | |
| SCHEMBL24818995 | 0.90 | CBLB (0.44) | CBLB | |
| SCHEMBL30152658 | 0.90 | CBLB (0.44) | CBLB | |
| SCHEMBL24819867 | 0.90 | VSIR (0.40) | CBLBCETPVSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |