Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | CBLB | Q13191 | 3/20 | 0.33 |
| ▸ | CBL | P22681 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.32 |
| ▸ | USP1 | O94782 | 2/20 | 0.32 |
| ▸ | USP8 | P40818 | 2/20 | 0.32 |
| ▸ | OTUB1 | Q96FW1 | 2/20 | 0.32 |
| ▸ | USP36 | Q9P275 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152796 | 1.00 | CHEK2 (0.35) | CHEK2METNOS3NOS1NOS2 | |
| SCHEMBL24819891 | 0.85 | SCN9A (0.35) | CBLBSCN9A | |
| SCHEMBL30152925 | 0.85 | SCN9A (0.35) | CBLBSCN9A | |
| SCHEMBL30153349 | 0.82 | ADORA2A (0.39) | HRH4 | |
| SCHEMBL24821802 | 0.82 | ADORA2A (0.39) | HRH4 | |
| SCHEMBL24818853 | 0.81 | SCD (0.35) | CBLBSCN9A | |
| SCHEMBL30152813 | 0.81 | SCD (0.35) | CBLBSCN9A | |
| SCHEMBL24819889 | 0.80 | CBLB (0.35) | CBLBCBLSCN9AUSP2 | |
| SCHEMBL24819888 | 0.80 | PIM1 (0.36) | CBLBCBLSCN9A | |
| SCHEMBL30153255 | 0.80 | CBLB (0.35) | CBLBCBLSCN9AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |