Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | IL17A | Q16552 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153349 | 1.00 | ADORA2A (0.39) | ADORA2AADORA1ACHEKDM4ESMN1; SMN2 | |
| SCHEMBL24819891 | 0.85 | SCN9A (0.35) | KDM4ESMN1; SMN2BACE1 | |
| SCHEMBL30152925 | 0.85 | SCN9A (0.35) | KDM4ESMN1; SMN2BACE1 | |
| SCHEMBL24820524 | 0.82 | CBLB (0.40) | ADORA2AADORA1 | |
| SCHEMBL24818783 | 0.82 | CHEK2 (0.35) | HRH4 | |
| SCHEMBL30152796 | 0.82 | CHEK2 (0.35) | HRH4 | |
| SCHEMBL24818853 | 0.81 | SCD (0.35) | BACE1 | |
| SCHEMBL30152813 | 0.81 | SCD (0.35) | BACE1 | |
| SCHEMBL29189995 | 0.81 | MCHR1 (0.41) | MCHR1 | |
| SCHEMBL24819889 | 0.80 | CBLB (0.35) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |