Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152678 | 0.91 | GUSB (0.36) | GUSBBACE1BACE2GAAMGAM | |
| SCHEMBL24818859 | 0.91 | GUSB (0.36) | GUSBBACE1BACE2GAAMGAM | |
| SCHEMBL30152881 | 0.86 | NPC1 (0.46) | BACE1BACE2GAAMGAMSI | |
| SCHEMBL24818670 | 0.86 | NPC1 (0.46) | BACE1BACE2GAAMGAMSI | |
| SCHEMBL24819848 | 0.85 | VSIR (0.39) | GUSBBACE1BACE2GAAMGAM | |
| SCHEMBL30152909 | 0.84 | VSIR (0.38) | GUSBBACE1BACE2GAAMGAM | |
| SCHEMBL24818669 | 0.84 | VSIR (0.38) | GUSBBACE1BACE2GAAMGAM | |
| SCHEMBL30152726 | 0.84 | BRD4 (0.40) | GUSBBACE1BACE2GAAMGAM | |
| SCHEMBL24818738 | 0.84 | BRD4 (0.40) | GUSBBACE1BACE2GAAMGAM | |
| SCHEMBL24818678 | 0.81 | CD274 (0.35) | VSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |