Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 11/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152909 | 1.00 | VSIR (0.38) | VSIRBACE1BACE2KDM4ECDK9 | |
| SCHEMBL24819848 | 0.93 | VSIR (0.39) | VSIRBACE1BACE2KDM4EGUSB | |
| SCHEMBL30152624 | 0.87 | CBLB (0.34) | VSIR | |
| SCHEMBL24820318 | 0.87 | CBLB (0.34) | VSIR | |
| SCHEMBL24818859 | 0.86 | GUSB (0.36) | VSIRBACE1BACE2KDM4EGUSB | |
| SCHEMBL30152678 | 0.86 | GUSB (0.36) | VSIRBACE1BACE2KDM4EGUSB | |
| SCHEMBL24818813 | 0.84 | GUSB (0.36) | VSIRBACE1BACE2KDM4EGUSB | |
| SCHEMBL30152902 | 0.83 | VSIR (0.41) | VSIRKDM4E | |
| SCHEMBL24819911 | 0.83 | VSIR (0.41) | VSIRKDM4E | |
| SCHEMBL24818678 | 0.81 | CD274 (0.35) | VSIRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |