Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 3/20 | 0.33 |
| ▸ | CBL | P22681 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818941 | 1.00 | CBLB (0.33) | CBLBCBLHTR3AVSIRMAP3K5 | |
| SCHEMBL24821954 | 0.88 | CBLB (0.33) | CBLBHTR3AVSIROPRK1 | |
| SCHEMBL24818680 | 0.86 | VSIR (0.35) | CBLBVSIR | |
| SCHEMBL24818891 | 0.86 | VSIR (0.35) | CBLBVSIR | |
| SCHEMBL24818917 | 0.86 | VSIR (0.35) | CBLBVSIR | |
| SCHEMBL24820761 | 0.86 | VSIR (0.35) | CBLBVSIR | |
| SCHEMBL24820642 | 0.85 | HTR3A (0.35) | HTR3A | |
| SCHEMBL30152835 | 0.85 | VSIR (0.33) | CBLBVSIR | |
| SCHEMBL24820025 | 0.85 | VSIR (0.35) | CBLBVSIR | |
| SCHEMBL24820029 | 0.85 | VSIR (0.35) | CBLBVSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |