Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.35 |
| ▸ | CBLB | Q13191 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818934 | 1.00 | VSIR (0.35) | VSIRCBLBALDH1A1CYP2D6CETP | |
| SCHEMBL24818945 | 1.00 | VSIR (0.35) | VSIRCBLBALDH1A1CYP2D6CETP | |
| SCHEMBL24818766 | 0.92 | VSIR (0.36) | VSIRALDH1A1CYP2D6CETP | |
| SCHEMBL30152786 | 0.92 | VSIR (0.36) | VSIRALDH1A1CYP2D6CETP | |
| SCHEMBL24819924 | 0.91 | VSIR (0.37) | VSIRCBLBCETP | |
| SCHEMBL24819883 | 0.89 | VSIR (0.42) | VSIRCBLBCETP | |
| SCHEMBL24820268 | 0.88 | VSIR (0.41) | VSIRCBLB | |
| SCHEMBL24820251 | 0.87 | VSIR (0.40) | VSIRCBLBCETP | |
| SCHEMBL24819928 | 0.87 | VSIR (0.35) | VSIRCBLBCETP | |
| SCHEMBL30153009 | 0.86 | CBLB (0.36) | VSIRCBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |