Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818766 | 1.00 | VSIR (0.36) | VSIRHPGDALDH1A1CYP2D6CETP | |
| SCHEMBL24818934 | 0.92 | VSIR (0.35) | VSIRALDH1A1CYP2D6CETP | |
| SCHEMBL24818945 | 0.92 | VSIR (0.35) | VSIRALDH1A1CYP2D6CETP | |
| SCHEMBL24818948 | 0.92 | VSIR (0.35) | VSIRALDH1A1CYP2D6CETP | |
| SCHEMBL24818740 | 0.88 | VSIR (0.44) | VSIRHPGDCETPTP53MAPT | |
| SCHEMBL24819032 | 0.87 | CBLB (0.34) | — | |
| SCHEMBL30152998 | 0.87 | CBLB (0.34) | — | |
| SCHEMBL30152960 | 0.87 | CBLB (0.34) | — | |
| SCHEMBL24821811 | 0.87 | CBLB (0.34) | — | |
| SCHEMBL29190093 | 0.84 | ALDH1A1 (0.34) | HPGDALDH1A1CYP2D6CETPTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |