Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381737 | 0.82 | NOTUM (0.47) | NOTUMTSHRMAPK1RAB9ANPC1 | |
| SCHEMBL3173819 | 0.82 | NOTUM (0.62) | NOTUMTSHRMAPK1RAB9ANPC1 | |
| SCHEMBL29541755 | 0.79 | NOTUM (0.62) | NOTUMTSHRMAPK1RAB9ANPC1 | |
| SCHEMBL26778468 | 0.76 | NOTUM (0.66) | NOTUMTSHRMAPK1RAB9ANPC1 | |
| SCHEMBL27918926 | 0.76 | RAB9A (0.49) | NOTUMTSHRMAPK1RAB9ANPC1 | |
| SCHEMBL30825423 | 0.74 | NOTUM (0.61) | NOTUMTSHRMAPK1RAB9ANPC1 | |
| SCHEMBL4221716 | 0.74 | NOTUM (0.61) | NOTUMTSHRMAPK1RAB9ANPC1 | |
| SCHEMBL30745985 | 0.72 | NOTUM (0.59) | NOTUMTSHRMAPK1RAB9ANPC1 | |
| SCHEMBL17148986 | 0.72 | NOTUM (0.59) | NOTUMTSHRMAPK1 | |
| SCHEMBL17148984 | 0.72 | NOTUM (0.59) | NOTUMTSHRMAPK1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |