Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 15/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148984 | 0.86 | NOTUM (0.59) | NOTUMNPC1RAB9ATSHRMAPK1 | |
| SCHEMBL29541755 | 0.82 | NOTUM (0.62) | NOTUMNPC1RAB9ATSHRMAPK1 | |
| SCHEMBL7992184 | 0.79 | NOTUM (0.59) | NOTUMNPC1RAB9ATSHRMAPK1 | |
| SCHEMBL31061827 | 0.79 | NOTUM (0.59) | NOTUMNPC1RAB9ATSHRMAPK1 | |
| SCHEMBL4381737 | 0.79 | NOTUM (0.47) | NOTUMNPC1RAB9ATSHRMAPK1 | |
| SCHEMBL27007671 | 0.78 | NPC1 (0.44) | NPC1RAB9ATSHRTP53SMN1; SMN2 | |
| SCHEMBL12909241 | 0.76 | NOTUM (0.53) | NOTUMNPC1RAB9ATSHRMAPK1 | |
| SCHEMBL7050954 | 0.74 | NOTUM (1.00) | NOTUMNPC1RAB9ATSHRMAPK1 | |
| SCHEMBL24819002 | 0.72 | NOTUM (0.53) | NOTUMNPC1RAB9ATSHRMAPK1 | |
| SCHEMBL25286035 | 0.72 | NPC1 (0.40) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMCIAL DIVERSITY CENTER, INC. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | ERG28, CYP51A1, MANBA | NOTUM 3119/4885NPC1 62/4885RAB9A 2076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.