Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23541226 | 1.00 | GHSR (0.35) | GHSRPRMT5GPR119TLR9TLR7 | |
| SCHEMBL31397309 | 1.00 | GHSR (0.35) | GHSRPRMT5GPR119TLR9TLR7 | |
| SCHEMBL23541225 | 1.00 | GHSR (0.35) | GHSRPRMT5GPR119TLR9TLR7 | |
| SCHEMBL29026388 | 0.91 | GRM5 (0.38) | GRM5BRD4CREBBP | |
| SCHEMBL23540926 | 0.86 | NAMPT (0.41) | PRMT5GPR119GRM5BRD4 | |
| SCHEMBL30026731 | 0.86 | GRM5 (0.35) | GRM5BRD4CREBBP | |
| SCHEMBL23541206 | 0.86 | GRM5 (0.35) | GRM5BRD4CREBBP | |
| SCHEMBL23541208 | 0.86 | GRM5 (0.35) | GRM5BRD4CREBBP | |
| SCHEMBL23540602 | 0.84 | BRD4 (0.34) | GRM5BRD4CREBBP | |
| SCHEMBL23540601 | 0.84 | BRD4 (0.34) | GRM5BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271727-A1 | DEGRADER COMPOUNDS AND USES THEREOF | CALICO LIFE SCIENCES LLC (US) | 2022-12-29 | — | — | WO | disclosed |