Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31397309 | 0.91 | GHSR (0.35) | GRM5BRD4CREBBP | |
| SCHEMBL23541226 | 0.91 | GHSR (0.35) | GRM5BRD4CREBBP | |
| SCHEMBL23541225 | 0.91 | GHSR (0.35) | GRM5BRD4CREBBP | |
| SCHEMBL24819532 | 0.91 | GHSR (0.35) | GRM5BRD4CREBBP | |
| SCHEMBL23541206 | 0.90 | GRM5 (0.35) | GRM5BRD4CREBBPPKMGLP1R | |
| SCHEMBL30026731 | 0.90 | GRM5 (0.35) | GRM5BRD4CREBBPPKMGLP1R | |
| SCHEMBL23541208 | 0.90 | GRM5 (0.35) | GRM5BRD4CREBBPPKMGLP1R | |
| SCHEMBL23540601 | 0.88 | BRD4 (0.34) | GRM5BRD4CREBBPPKMGLP1R | |
| SCHEMBL23540602 | 0.88 | BRD4 (0.34) | GRM5BRD4CREBBPPKMGLP1R | |
| SCHEMBL23541280 | 0.84 | ADORA3 (0.35) | GRM5BRD4CREBBPPKMADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194453-A | Protein tyrosine phosphatase degrading agent and method of use thereof | 卡里科生命科学有限责任公司 | 2023-05-30 | — | — | CN | disclosed |