Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 9/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24819815 | 1.00 | TRPV3 (0.39) | TRPV3LTA4HCCR2ALDH1A1GAA | |
| SCHEMBL24819836 | 1.00 | TRPV3 (0.39) | TRPV3LTA4HCCR2ALDH1A1GAA | |
| SCHEMBL24819835 | 1.00 | TRPV3 (0.39) | TRPV3LTA4HCCR2ALDH1A1GAA | |
| SCHEMBL24819837 | 1.00 | TRPV3 (0.39) | TRPV3LTA4HCCR2ALDH1A1GAA | |
| SCHEMBL24818414 | 0.94 | ALDH1A1 (0.32) | TRPV3ALDH1A1GAAMAPTALOX15 | |
| SCHEMBL24821771 | 0.91 | TRPV3 (0.34) | TRPV3LTA4HALDH1A1GAAMAPT | |
| SCHEMBL24821763 | 0.91 | TRPV3 (0.34) | TRPV3LTA4HALDH1A1GAAMAPT | |
| SCHEMBL24821770 | 0.91 | TRPV3 (0.34) | TRPV3LTA4HALDH1A1GAAMAPT | |
| SCHEMBL24818514 | 0.89 | ALDH1A1 (0.38) | TRPV3LTA4HALDH1A1GAAMAPT | |
| SCHEMBL24818506 | 0.89 | ALDH1A1 (0.38) | TRPV3LTA4HALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |