SCHEMBL24819929

SCHEMBL24819929

COCCNCc1cc(C(F)(F)F)c2[nH]c(-c3cc(-c4ccc(F)cc4-c4nncn4C)cc(C4CC4)n3)nc2c1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30152959 1.00 CBLB (0.42) CBLB
SCHEMBL24820706 0.87 CBLB (0.39) CBLB
SCHEMBL30152762 0.87 CBLB (0.39) CBLB
SCHEMBL30152542 0.86 CBLB (0.42) CBLB
SCHEMBL24820272 0.86 CBLB (0.42) CBLB
SCHEMBL24821922 0.85 CBLB (0.41) CBLB
SCHEMBL30152826 0.85 CBLB (0.41) CBLB
SCHEMBL24821926 0.83 CBLB (0.38) CBLB
SCHEMBL30152801 0.83 CBLB (0.38) CBLB
SCHEMBL24818903 0.82 CBLB (0.39) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858865-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 — — CN disclosed
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 — — WO disclosed
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