SCHEMBL24821926

SCHEMBL24821926

Cn1cnnc1-c1cc(F)ccc1-c1cc(-c2nc3cc(C=O)cc(C(F)(F)F)c3[nH]2)nc(C2CC2)c1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30152801 1.00 CBLB (0.38) CBLB
SCHEMBL24818978 0.89 HSD11B1 (0.30) —
SCHEMBL30153170 0.89 HSD11B1 (0.30) —
SCHEMBL30152762 0.87 CBLB (0.39) CBLB
SCHEMBL24820706 0.87 CBLB (0.39) CBLB
SCHEMBL24821950 0.86 BRD4 (0.37) CBLB
SCHEMBL30153162 0.86 BRD4 (0.37) CBLB
SCHEMBL24818742 0.85 CBLB (0.34) CBLB
SCHEMBL30152621 0.85 CBLB (0.34) CBLB
SCHEMBL24818958 0.84 CBLB (0.38) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 — — WO disclosed
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