Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 8/20 | 0.34 |
| ▸ | VSIR | Q9H7M9 | 7/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152728 | 1.00 | CBLB (0.44) | CBLBITKCETPVSIRPDCD1 | |
| SCHEMBL24819873 | 0.90 | CBLB (0.34) | CBLBCETPVSIRPDCD1CD274 | |
| SCHEMBL30152520 | 0.89 | CBLB (0.46) | CBLBITKCETPPPARG | |
| SCHEMBL24821767 | 0.89 | CBLB (0.46) | CBLBITKCETPPPARG | |
| SCHEMBL30153100 | 0.87 | CBLB (0.42) | CBLBCETPPDCD1CD274PPARG | |
| SCHEMBL30152718 | 0.87 | CBLB (0.42) | CBLBCETPPPARGPDE10A | |
| SCHEMBL24820594 | 0.87 | CBLB (0.42) | CBLBCETPPPARGPDE10A | |
| SCHEMBL24820602 | 0.87 | CBLB (0.42) | CBLBCETPPDCD1CD274PPARG | |
| SCHEMBL24820567 | 0.83 | CBLB (0.41) | CBLBCETP | |
| SCHEMBL30153017 | 0.83 | CBLB (0.41) | CBLBCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |