Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153017 | 1.00 | CBLB (0.41) | CBLBHDAC6CETPMAPTRAB9A | |
| SCHEMBL30792199 | 1.00 | CBLB (0.41) | CBLBHDAC6CETPMAPTRAB9A | |
| SCHEMBL30152867 | 0.89 | MAPT (0.38) | HDAC6MAPTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL24820737 | 0.89 | AGPAT2 (0.38) | HDAC6MAPTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL24818763 | 0.89 | MAPT (0.38) | HDAC6MAPTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL30792049 | 0.89 | AGPAT2 (0.38) | HDAC6MAPTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL30792132 | 0.89 | MAPT (0.38) | HDAC6MAPTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL24818967 | 0.88 | CBLB (0.41) | CBLBCETPSMN1; SMN2CYP11B2KDM4E | |
| SCHEMBL30792053 | 0.88 | CBLB (0.41) | CBLBCETPSMN1; SMN2CYP11B2KDM4E | |
| SCHEMBL30153054 | 0.88 | CBLB (0.41) | CBLBCETPSMN1; SMN2CYP11B2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |