Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 19/20 | 0.61 |
| ▸ | CBL | P22681 | 15/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152679 | 1.00 | CBLB (0.61) | CBLBCBLCNR2 | |
| SCHEMBL31757983 | 0.85 | CBLB (0.62) | CBLBCBL | |
| SCHEMBL30152592 | 0.85 | CBLB (0.61) | CBLBCBL | |
| SCHEMBL24821819 | 0.85 | CBLB (0.61) | CBLBCBL | |
| SCHEMBL26481237 | 0.83 | CBLB (0.64) | CBLBCBL | |
| SCHEMBL24818540 | 0.82 | CBLB (0.44) | CBLBCNR2 | |
| SCHEMBL30152606 | 0.82 | CBLB (0.44) | CBLBCNR2 | |
| SCHEMBL24818544 | 0.82 | CBLB (0.44) | CBLBCNR2 | |
| SCHEMBL30152768 | 0.82 | CBLB (0.44) | CBLBCNR2 | |
| SCHEMBL24818660 | 0.80 | CBLB (0.42) | CBLBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |