Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | UTRN | P46939 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153081 | 1.00 | HDAC3 (0.33) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30153113 | 0.88 | — | — | |
| SCHEMBL30153166 | 0.88 | CBLB (0.33) | HSD11B1S1PR1FASN | |
| SCHEMBL24820113 | 0.88 | — | — | |
| SCHEMBL24818907 | 0.88 | CBLB (0.33) | HSD11B1S1PR1FASN | |
| SCHEMBL24818801 | 0.87 | UTRN (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30152971 | 0.85 | S1PR1 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL24819948 | 0.85 | S1PR1 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL24820486 | 0.85 | CBLB (0.33) | S1PR1S1PR3 | |
| SCHEMBL30153074 | 0.85 | CBLB (0.33) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |