Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 5/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153074 | 1.00 | CBLB (0.33) | CBLBNOTUMS1PR1S1PR3 | |
| SCHEMBL24820113 | 0.91 | — | — | |
| SCHEMBL30153113 | 0.91 | — | — | |
| SCHEMBL30152601 | 0.89 | CBLB (0.38) | CBLBNOTUM | |
| SCHEMBL24818958 | 0.89 | CBLB (0.38) | CBLBNOTUM | |
| SCHEMBL24818753 | 0.88 | VSIR (0.34) | CBLBS1PR1 | |
| SCHEMBL30153198 | 0.85 | CETP (0.33) | CBLBNOTUMS1PR1S1PR3 | |
| SCHEMBL24820485 | 0.85 | CETP (0.33) | CBLBNOTUMS1PR1S1PR3 | |
| SCHEMBL24820101 | 0.85 | HDAC3 (0.33) | S1PR1S1PR3 | |
| SCHEMBL30153081 | 0.85 | HDAC3 (0.33) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |