Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 4/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818907 | 1.00 | CBLB (0.33) | CBLBMAP3K5HSD11B1F2RL3S1PR1 | |
| SCHEMBL24820110 | 0.91 | KDM4E (0.34) | CBLBF2RL3 | |
| SCHEMBL30153103 | 0.88 | CBLB (0.42) | CBLBMAP3K5 | |
| SCHEMBL24820565 | 0.88 | CBLB (0.42) | CBLBMAP3K5 | |
| SCHEMBL30152563 | 0.88 | CBLB (0.33) | CBLBMAP3K5 | |
| SCHEMBL30152962 | 0.88 | CBLB (0.33) | CBLBMAP3K5 | |
| SCHEMBL24818771 | 0.88 | CBLB (0.33) | CBLBMAP3K5 | |
| SCHEMBL24819033 | 0.88 | CBLB (0.33) | CBLBMAP3K5 | |
| SCHEMBL24820101 | 0.88 | HDAC3 (0.33) | HSD11B1S1PR1FASN | |
| SCHEMBL30153081 | 0.88 | HDAC3 (0.33) | HSD11B1S1PR1FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |