Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243199 | 0.94 | CA1 (0.42) | HTTCA1CA2CA4ACHE | |
| SCHEMBL22563652 | 0.83 | — | — | |
| SCHEMBL9810899 | 0.83 | CA1 (0.39) | CA1CA2CA4KMT2A | |
| SCHEMBL1460586 | 0.82 | S1PR1 (0.40) | CA1CA2CA4 | |
| SCHEMBL17591686 | 0.80 | S1PR1 (0.42) | — | |
| SCHEMBL1664270 | 0.79 | NAAA (0.44) | — | |
| SCHEMBL12809361 | 0.77 | KDM1A (0.35) | CA1CA2 | |
| SCHEMBL24819077 | 0.76 | CA2 (0.34) | HTTCA1CA2CA4KMT2A | |
| SCHEMBL24819083 | 0.76 | CA2 (0.34) | HTTCA1CA2CA4KMT2A | |
| SCHEMBL24819080 | 0.76 | CA2 (0.34) | HTTCA1CA2CA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |