Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24368979 | 1.00 | PIK3CD (0.37) | PIK3CDPDE10AWNT1GSK3BDYRK1A | |
| SCHEMBL23374669 | 1.00 | PIK3CD (0.37) | PIK3CDPDE10AWNT1GSK3BDYRK1A | |
| SCHEMBL4326980 | 0.85 | PDE10A (0.31) | PDE10A | |
| SCHEMBL22661910 | 0.83 | WNT1 (0.33) | PDE10AWNT1GSK3BDYRK1A | |
| SCHEMBL25702634 | 0.83 | WNT1 (0.33) | PDE10AWNT1GSK3BDYRK1A | |
| SCHEMBL23074743 | 0.80 | GBA1 (0.36) | PDE10A | |
| SCHEMBL15699287 | 0.80 | GBA1 (0.36) | PDE10A | |
| SCHEMBL4983910 | 0.80 | PDE10A (0.33) | PDE10A | |
| SCHEMBL23074745 | 0.80 | GBA1 (0.36) | PDE10A | |
| SCHEMBL2071897 | 0.80 | PDE10A (0.33) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |