Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 8/20 | 0.40 |
| ▸ | CBL | P22681 | 4/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
| ▸ | ROS1 | P08922 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153116 | 1.00 | CBLB (0.40) | CBLBCBLPDE2AMAP3K5ROS1 | |
| SCHEMBL24818633 | 0.86 | CBLB (0.42) | CBLBCBLPDE2A | |
| SCHEMBL30153041 | 0.86 | CBLB (0.42) | CBLBCBLPDE2A | |
| SCHEMBL30153008 | 0.76 | CBLB (0.45) | CBLBPDE2AMAP3K5ROS1 | |
| SCHEMBL24818719 | 0.76 | CBLB (0.45) | CBLBPDE2AMAP3K5ROS1 | |
| SCHEMBL24820612 | 0.75 | CBLB (0.37) | CBLBPDE2AROS1 | |
| SCHEMBL24818748 | 0.75 | CBLB (0.43) | CBLBROS1 | |
| SCHEMBL29920812 | 0.75 | CBLB (0.43) | CBLBROS1 | |
| SCHEMBL24819939 | 0.74 | CBLB (0.45) | CBLBPDE2AROS1 | |
| SCHEMBL24820618 | 0.74 | CBLB (0.45) | CBLBPDE2AROS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |