Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP5 | P51878 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | CASP4 | P49662 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820413 | 0.89 | CYP3A4 (0.46) | ALDH1A1CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL24820406 | 0.86 | CNR2 (0.44) | KDM4EALDH1A1CNR2 | |
| SCHEMBL24820408 | 0.86 | CNR2 (0.44) | KDM4EALDH1A1CNR2 | |
| SCHEMBL24820420 | 0.86 | CNR2 (0.44) | KDM4EALDH1A1CNR2 | |
| SCHEMBL24820418 | 0.84 | CYP3A4 (0.42) | ALDH1A1CYP3A4CYP2D6MEN1TP53 | |
| SCHEMBL24818541 | 0.83 | TSHR (0.36) | KDM4ECYP3A4CYP2D6MEN1TP53 | |
| SCHEMBL24820338 | 0.83 | ALDH1A1 (0.44) | KDM4EALDH1A1GAACNR2 | |
| SCHEMBL24820342 | 0.83 | ALDH1A1 (0.44) | KDM4EALDH1A1GAACNR2 | |
| SCHEMBL24820340 | 0.83 | ALDH1A1 (0.44) | KDM4EALDH1A1GAACNR2 | |
| SCHEMBL24821727 | 0.78 | MAPT (0.39) | KDM4EGAAS1PR1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |