Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820340 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4ECD274PDCD1 | |
| SCHEMBL24820338 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4ECD274PDCD1 | |
| SCHEMBL24820420 | 0.84 | CNR2 (0.44) | ALDH1A1KDM4ECNR2PDE2A | |
| SCHEMBL24820406 | 0.84 | CNR2 (0.44) | ALDH1A1KDM4ECNR2PDE2A | |
| SCHEMBL24820408 | 0.84 | CNR2 (0.44) | ALDH1A1KDM4ECNR2PDE2A | |
| SCHEMBL24820334 | 0.83 | SIGMAR1 (0.42) | ALDH1A1GAAKDM4ECNR2 | |
| SCHEMBL24820421 | 0.81 | CNR2 (0.44) | CNR2PIK3CDMTORPIK3CGPDE5A | |
| SCHEMBL24820403 | 0.81 | CNR2 (0.44) | CNR2PIK3CDMTORPIK3CGPDE5A | |
| SCHEMBL24820412 | 0.81 | CNR2 (0.44) | CNR2PIK3CDMTORPIK3CGPDE5A | |
| SCHEMBL24820413 | 0.80 | CYP3A4 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |