Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15314574 | 0.74 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1GAA | |
| SCHEMBL24819116 | 0.72 | MAPT (0.30) | — | |
| SCHEMBL13297129 | 0.72 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL24819113 | 0.72 | MAPT (0.30) | — | |
| SCHEMBL10205040 | 0.69 | GAA (0.31) | ALDH1A1L3MBTL1GAA | |
| SCHEMBL13297134 | 0.69 | — | — | |
| SCHEMBL6628245 | 0.69 | — | — | |
| SCHEMBL27368017 | 0.68 | GAA (0.30) | GAA | |
| SCHEMBL22725306 | 0.67 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1GAA | |
| SCHEMBL18607993 | 0.67 | HSD11B1 (0.36) | HSD11B1ALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |