Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778093 | 0.80 | ADH1B (0.39) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL20069405 | 0.79 | MEN1 (0.33) | ANPEP | |
| SCHEMBL18244860 | 0.78 | ADH1B (0.38) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL1005943 | 0.76 | ADH1B (0.45) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL23189474 | 0.76 | ADH1B (0.36) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL25020574 | 0.75 | CHRNB2 (0.45) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL18236737 | 0.75 | — | — | |
| SCHEMBL80772 | 0.74 | ANPEP (0.40) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL18756188 | 0.74 | ANPEP (0.40) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL80162 | 0.74 | ANPEP (0.40) | ADH1BADH1CADH1AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |