SCHEMBL29190056

SCHEMBL29190056

CCNc1cc(-c2ccccc2-c2nncn2C)cc(C(=O)Nc2cc(CO)cc(C(F)(F)F)c2N)n1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30153246 1.00 CBLB (0.37) CBLB
SCHEMBL30152871 0.88 CBLB (0.39) CBLB
SCHEMBL30152651 0.85 CBLB (0.40) CBLB
SCHEMBL24820513 0.82 CBLB (0.37) CBLB
SCHEMBL30152659 0.82 CBLB (0.37) CBLB
SCHEMBL24818718 0.79 CBLB (0.47) CBLB
SCHEMBL24820707 0.79 CBLB (0.41) CBLB
SCHEMBL30152907 0.79 CBLB (0.41) CBLB
SCHEMBL30153213 0.78 CBLB (0.37) CBLB
SCHEMBL30792214 0.78 MAP3K5 (0.36) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858865-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 — — CN disclosed
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