Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 6/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2072379 | 0.81 | NAAA (0.50) | NAAAASAH1 | |
| SCHEMBL2071214 | 0.80 | ASAH1 (0.57) | ASAH1DAOLMNACYP3A4CYP2D6 | |
| SCHEMBL2072861 | 0.79 | ASAH1 (0.47) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL2072875 | 0.71 | ASAH1 (0.44) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL16651781 | 0.69 | GPR84 (0.50) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL25002728 | 0.69 | NAMPT (0.75) | NAAA | |
| SCHEMBL15537832 | 0.69 | ASAH1 (0.79) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL15537508 | 0.69 | ASAH1 (0.78) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL15538232 | 0.69 | ASAH1 (0.54) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL16652149 | 0.68 | GPR84 (0.49) | ASAH1LMNACYP3A4CYP2D6MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001878-B1 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES AS INHIBITORS OF ENDOTHELIAL LIPASE | SANOFI SA (FR) | 2011-10-12 | — | — | EP | disclosed |