Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 20/20 | 0.41 |
| ▸ | CBL | P22681 | 19/20 | 0.41 |
| ▸ | CBLC | Q9ULV8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153197 | 0.88 | CBLB (0.54) | CBLBCBLCBLC | |
| SCHEMBL24820655 | 0.87 | CBLB (0.41) | CBLBCBLCBLC | |
| SCHEMBL24818936 | 0.78 | CBL (0.32) | CBLBCBL | |
| SCHEMBL24818908 | 0.76 | CBLB (0.39) | CBLBCBL | |
| SCHEMBL30153109 | 0.75 | CBLB (0.53) | CBLBCBLCBLC | |
| SCHEMBL30153254 | 0.74 | CBLB (0.37) | CBLB | |
| SCHEMBL24820501 | 0.74 | CBLB (0.37) | CBLB | |
| SCHEMBL30152954 | 0.73 | CBLB (0.51) | CBLBCBLCBLC | |
| SCHEMBL24819910 | 0.73 | CBLB (0.51) | CBLBCBLCBLC | |
| SCHEMBL30792112 | 0.73 | CBLB (0.51) | CBLBCBLCBLC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |