Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBL | P22681 | 5/20 | 0.32 |
| ▸ | CBLB | Q13191 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818909 | 0.86 | ESR1 (0.33) | CBLCBLB | |
| SCHEMBL24818935 | 0.86 | S1PR1 (0.34) | CBLCBLB | |
| SCHEMBL24820656 | 0.85 | CETP (0.33) | CBLCBLB | |
| SCHEMBL30153197 | 0.80 | CBLB (0.54) | CBLCBLB | |
| SCHEMBL24818937 | 0.80 | TRPV3 (0.33) | CBLB | |
| SCHEMBL24821925 | 0.78 | CBLB (0.41) | CBLCBLB | |
| SCHEMBL24820501 | 0.77 | CBLB (0.37) | CBLB | |
| SCHEMBL30153254 | 0.77 | CBLB (0.37) | CBLB | |
| SCHEMBL24818927 | 0.75 | DRD2 (0.31) | CBLCBLB | |
| SCHEMBL24818753 | 0.74 | VSIR (0.34) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |