SCHEMBL30792112

SCHEMBL30792112

COC(=O)c1cc(C(F)(F)F)c2oc(-c3cccc(C4(c5nncn5C)CC(C)C4)c3)nc2c1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.51
▸ CBL P22681 18/20 0.51
▸ CBLC Q9ULV8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30152954 1.00 CBLB (0.51) CBLBCBLCBLC
SCHEMBL24819910 1.00 CBLB (0.51) CBLBCBLCBLC
SCHEMBL30792016 0.89 CBLB (0.50) CBLBCBLCBLC
SCHEMBL30152674 0.89 CBLB (0.50) CBLBCBLCBLC
SCHEMBL30153109 0.86 CBLB (0.53) CBLBCBLCBLC
SCHEMBL30153197 0.85 CBLB (0.54) CBLBCBLCBLC
SCHEMBL30153030 0.82 CBLB (0.47) CBLBCBLCBLC
SCHEMBL30963773 0.82 CBLB (0.49) CBLBCBLCBLC
SCHEMBL24820656 0.81 CETP (0.33) CBLBCBL
SCHEMBL24819917 0.81 CBLB (0.47) CBLBCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858865-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 — — CN disclosed
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