Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153162 | 1.00 | BRD4 (0.37) | BRD4SSTR2KCNH2CBLBMAP3K5 | |
| SCHEMBL24820080 | 0.86 | SSTR2 (0.34) | SSTR2KCNH2CBLBMAP3K5 | |
| SCHEMBL30153169 | 0.86 | SSTR2 (0.34) | SSTR2KCNH2CBLBMAP3K5 | |
| SCHEMBL30152801 | 0.86 | CBLB (0.38) | CBLB | |
| SCHEMBL24821926 | 0.86 | CBLB (0.38) | CBLB | |
| SCHEMBL24820081 | 0.85 | BRD4 (0.40) | BRD4SSTR2KCNH2CBLBMAP3K5 | |
| SCHEMBL30152703 | 0.85 | BRD4 (0.40) | BRD4SSTR2KCNH2CBLBMAP3K5 | |
| SCHEMBL24818738 | 0.84 | BRD4 (0.40) | BRD4 | |
| SCHEMBL30152726 | 0.84 | BRD4 (0.40) | BRD4 | |
| SCHEMBL24818907 | 0.82 | CBLB (0.33) | CBLBMAP3K5HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |