Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 14/20 | 0.76 |
| ▸ | NPC1 | O15118 | 7/20 | 0.71 |
| ▸ | RAB9A | P51151 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | DHODH | Q02127 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2485047 | 0.86 | SCD (0.82) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4912951 | 0.86 | SCD (1.00) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL3347489 | 0.85 | MAP3K5 (0.63) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL31065 | 0.85 | SCD (1.00) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL3346882 | 0.85 | SMN1; SMN2 (0.66) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16681363 | 0.85 | SCD (0.88) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL31243 | 0.84 | SCD (1.00) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL30917 | 0.83 | SCD (0.83) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4919127 | 0.82 | SCD (1.00) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16554160 | 0.82 | SCD (1.00) | SCDNPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376463-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | Bayer Pharma Aktiengesellschaft (DE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |