Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 9/20 | 0.60 |
| ▸ | RAB9A | P51151 | 9/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KLK7 | P49862 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348554 | 0.85 | MAP3K5 (0.72) | MAP3K5NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2482233 | 0.85 | SCD (0.76) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5713530 | 0.85 | MAP3K5 (0.75) | MAP3K5NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8127125 | 0.84 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13329390 | 0.82 | MAP3K5 (0.83) | MAP3K5NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12199338 | 0.80 | HPGDS (0.69) | MAP3K5NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14807002 | 0.80 | MEN1 (0.72) | MAP3K5NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13329187 | 0.80 | HPGDS (0.69) | MAP3K5NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3346882 | 0.80 | SMN1; SMN2 (0.66) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2483622 | 0.79 | MAP3K5 (0.77) | MAP3K5NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |