SCHEMBL248224

SCHEMBL248224

C=CCCc1ccc(Cl)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.50
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
MAPK1 P28482 1/20 0.48
CYP2C19 P33261 1/20 0.48
PDPK1 O15530 1/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
CNR1 P21554 1/20 0.41
HPGD P15428 2/20 0.40
POLB P06746 1/20 0.40
GPR84 Q9NQS5 1/20 0.40
DAO P14920 1/20 0.40
GGPS1 O95749 1/20 0.40
HTT P42858 1/20 0.40
TP53 P04637 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30271268 1.00 IDO1 (0.50) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL8802702 0.89 IDO1 (0.47) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL246297 0.87 IDO1 (0.46) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL9156971 0.85 ACLY (0.46) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL20095950 0.81 HTT (0.41) IDO1MAPK1HPGDHTTTP53
SCHEMBL11621292 0.80 IDO1 (0.65) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL432703 0.80 IDO1 (0.50) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL585624 0.80 IDO1 (0.50) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL30956678 0.79 IDO1 (0.54) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL249746 0.79 IDO1 (0.54) IDO1CYP1A2CYP3A4CYP2C9MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115957725-A Modified hollow ceramic fiber and preparation method and application thereof 中国石油化工股份有限公司 2023-04-14 CN claimed
CN-115957616-A Desulfurization filler and preparation and application thereof 中国石油化工股份有限公司 2023-04-14 CN claimed
CN-115957616-A Desulfurization filler and preparation and application thereof 中国石油化工股份有限公司 2023-04-14 CN disclosed
CN-115957725-A Modified hollow ceramic fiber and preparation method and application thereof 中国石油化工股份有限公司 2023-04-14 CN disclosed
CN-109939092-B Phenyl carbamate compounds for use in preventing or treating pediatric epilepsy and epilepsy-related syndrome 比皮艾思药物研发有限公司 2022-03-22 CN disclosed
CN-105188690-B Phenyl carbamate compounds for use in preventing or treating movement disorders 比皮艾思药物研发有限公司 2020-06-12 CN disclosed
CN-105188689-B Phenyl carbamate compounds for use in preventing or treating epilepsy and epilepsy-related syndromes 比皮艾思药物研发有限公司 2020-04-10 CN disclosed
CN-105164103-B Phenyl carbamate compounds and composition for preventing or treating memory loss-related diseases containing the same 比皮艾思药物研发有限公司 2019-12-06 CN disclosed
CN-110478343-A Phenyl carbamate compound and comprising the compound for preventing or treating the composition of disease caused by nerve gas BIO PHARM SOLUTIONS CO LTD 2019-11-22 CN disclosed
CN-105189450-B Phenyl carbamate compound and composition for preventing or treating mental disorder comprising the same 比皮艾思药物研发有限公司 2019-09-13 CN disclosed
CN-105209430-B Phenyl carbamate compounds and neuroprotective compositions comprising the same 比皮艾思药物研发有限公司 2019-09-13 CN disclosed
WO-2013100568-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed
WO-2013100571-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING ALS BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed
WO-2013100566-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed
EP-2590936-A2 PHENYLCARBAMATE COMPOUND AND MUSCLE RELAXANT CONTAINING THE SAME Bio-Pharm Solutions Co., Ltd. (KR) 2013-05-15 EP disclosed
WO-2012096458-A2 PROCESS FOR PREPARATION OF PHENYL CARBAMATE DERIVATIVES BIO-PHARM SOLUTIONS CO., LTD. (KR) 2012-07-19 WO disclosed
WO-2012002773-A2 PHENYLCARBAMATE COMPOUND AND MUSCLE RELAXANT CONTAINING THE SAME BIO-PHARM SOLUTIONS CO., LTD. (KR) 2012-01-05 WO disclosed
EP-0492474-B1 1,3-Dioxolane derivatives as cholesterol-lowering agents SYNTEX INC (US) 1997-03-05 EP disclosed
US-5158949-A 1,3-DIOXOLANE DERIVATIVES AS CHOLESTEROL-LOWERING AGENTS SYNTEX (U.S.A.) INC. (US) 1992-10-27 US disclosed
EP-0492474-A1 1,3-Dioxolane derivatives as cholesterol-lowering agents SYNTEX (U.S.A.) INC. (US) 1992-07-01 EP disclosed