Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24823232 | 0.93 | OPRL1 (0.43) | ALDH1A1SMN1; SMN2OPRL1FOLH1OPRD1 | |
| SCHEMBL27268237 | 0.93 | OPRL1 (0.43) | ALDH1A1SMN1; SMN2OPRL1FOLH1OPRD1 | |
| SCHEMBL26030700 | 0.93 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2OPRL1FOLH1OPRD1 | |
| SCHEMBL23515709 | 0.93 | FOLH1 (0.43) | ALDH1A1SMN1; SMN2OPRL1FOLH1OPRD1 | |
| SCHEMBL27390781 | 0.92 | OPRL1 (0.43) | ALDH1A1SMN1; SMN2OPRL1FOLH1OPRD1 | |
| SCHEMBL22969978 | 0.92 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2OPRL1FOLH1OPRD1 | |
| SCHEMBL22969979 | 0.88 | OPRL1 (0.40) | ALDH1A1SMN1; SMN2OPRL1FOLH1OPRD1 | |
| SCHEMBL23515689 | 0.88 | OPRL1 (0.39) | ALDH1A1SMN1; SMN2OPRL1FOLH1OPRD1 | |
| SCHEMBL23680160 | 0.87 | OPRL1 (0.42) | ALDH1A1SMN1; SMN2OPRL1FOLH1OPRD1 | |
| SCHEMBL17029464 | 0.86 | FAAH (0.41) | OPRL1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268202-A1 | LIGAND-DRUG CONJUGATE AND USE THEREOF | 同宜医药（苏州）有限公司 | 2022-12-29 | — | — | WO | disclosed |