Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14186230 | 0.82 | CCR1 (0.53) | CCR1CCR5CCR8OPRM1OPRL1 | |
| SCHEMBL30997801 | 0.80 | CCR1 (0.54) | CCR1CCR5CCR8OPRM1OPRL1 | |
| SCHEMBL3391357 | 0.80 | CCR1 (0.54) | CCR1CCR5CCR8OPRM1OPRL1 | |
| SCHEMBL827860 | 0.80 | CCR1 (0.54) | CCR1CCR5CCR8OPRM1OPRL1 | |
| SCHEMBL24823782 | 0.77 | CHRNA7 (0.43) | CCR1CCR5CCR8OPRM1OPRL1 | |
| SCHEMBL13805980 | 0.77 | CCR1 (0.50) | CCR1CCR5CCR8OPRM1OPRL1 | |
| SCHEMBL13271138 | 0.77 | KDM4E (0.50) | CCR1CCR5CCR8OPRM1OPRL1 | |
| SCHEMBL13063398 | 0.76 | MAP3K12 (0.45) | NOS3NOS2 | |
| SCHEMBL24316513 | 0.76 | KDM4E (0.53) | CCR1CCR5CCR8OPRM1OPRL1 | |
| SCHEMBL24316619 | 0.76 | KDM4E (0.53) | CCR1CCR5CCR8OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |