Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4569947 | 0.82 | CHRNA7 (0.47) | CHRNA7MAP3K12OPRM1OPRL1TLR9 | |
| SCHEMBL15999369 | 0.78 | CHRNA7 (0.44) | CHRNA7MAP3K12TLR9TLR8TLR7 | |
| SCHEMBL22545236 | 0.78 | CHRNA7 (0.44) | CHRNA7MAP3K12CCNT1CDK9TLR9 | |
| SCHEMBL24823772 | 0.77 | CCR1 (0.52) | OPRM1OPRL1CCR1CCR5CCR8 | |
| SCHEMBL15999346 | 0.75 | CHRNA7 (0.42) | CHRNA7MAP3K12TLR9TLR8TLR7 | |
| SCHEMBL25147093 | 0.73 | CHRNA7 (0.40) | CHRNA7MAP3K12TLR9TLR8TLR7 | |
| SCHEMBL13063398 | 0.72 | MAP3K12 (0.45) | MAP3K12 | |
| SCHEMBL25135431 | 0.71 | CHRNA7 (0.39) | CHRNA7TLR9TLR8TLR7 | |
| SCHEMBL4569944 | 0.70 | CHRNA7 (0.43) | CHRNA7 | |
| SCHEMBL25692679 | 0.70 | HRH4 (0.41) | MAP3K12CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |